Tage Kemp 28/VIII/1896 – 7/1/1964

TAGE-SC-L Branch Predictors∗

The TAGE predictor [12] is considered as one of the most storage effective global branch/path history predictors. It has been shown that associated with small adjunct predictors like a statistical corrector (SC for short) and/or a loop predictor (L for short) [11, 10], TAGE can even be more effective. In this study, we explore the performance limits of these TAGE-SC-L predictors for respectivel...

A redox-mediated Kemp eliminase

The acid/base-catalysed Kemp elimination of 5-nitro-benzisoxazole forming 2-cyano-4-nitrophenol has long served as a design platform of enzymes with non-natural reactions, providing new mechanistic insights in protein science. Here we describe an alternative concept based on redox catalysis by P450-BM3, leading to the same Kemp product via a fundamentally different mechanism. QM/MM computations...

The L-TAGE Branch Predictor

Kemp Eliminase Activity of Ketosteroid Isomerase.

Kemp eliminases represent the most successful class of computationally designed enzymes, with rate accelerations of up to 109-fold relative to the rate of the same reaction in aqueous solution. Nevertheless, several other systems such as micelles, catalytic antibodies, and cavitands are known to accelerate the Kemp elimination by several orders of magnitude. We found that the naturally occurrin...

Die 1 . Oldenburger Kul - Tour - Tage

Mit Namen gezeichnete Artikel geben die personliche Meinung des Verfassers wieder. Nachdruck aller Beiträge nur nach Rücksprache mit der Redaktion Der Gründlingsausschuß für die Universität Oldenburg, das Konzil und der Senat der Universität Oldenburg haben einstimmig beschlossen, daß die Universität Oldenburg den Namen Carl-von-Ossietzky-Universitäl fuhrt. Die Universität bedauert, daß ihr die...